PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29960031-0 2018 A new xanthatin analogue 1beta-hydroxyl-5alpha-chloro-8-epi-xanthatin induces apoptosis through ROS-mediated ERK/p38 MAPK activation and JAK2/STAT3 inhibition in human hepatocellular carcinoma. Reactive Oxygen Species 96-99 mitogen-activated protein kinase 1 Homo sapiens 109-112 29960031-0 2018 A new xanthatin analogue 1beta-hydroxyl-5alpha-chloro-8-epi-xanthatin induces apoptosis through ROS-mediated ERK/p38 MAPK activation and JAK2/STAT3 inhibition in human hepatocellular carcinoma. Reactive Oxygen Species 96-99 mitogen-activated protein kinase 1 Homo sapiens 117-121 29960031-6 2018 ROS scavenger N-acetyl cysteine abrogated the effects of XTT on ERK/p38 MAPK activation and JAK2/STAT3 inhibition, and rescued HCC cells from XTT-induced apoptosis. Reactive Oxygen Species 0-3 mitogen-activated protein kinase 1 Homo sapiens 64-67 29960031-6 2018 ROS scavenger N-acetyl cysteine abrogated the effects of XTT on ERK/p38 MAPK activation and JAK2/STAT3 inhibition, and rescued HCC cells from XTT-induced apoptosis. Reactive Oxygen Species 0-3 mitogen-activated protein kinase 1 Homo sapiens 72-76 29960031-8 2018 In summary, XTT inhibited cell growth and induced apoptosis in HCC cells through ROS-mediated ERK/p38 MAPK activation and JAK2/STAT3 inhibition by GSH depletion. Reactive Oxygen Species 81-84 mitogen-activated protein kinase 1 Homo sapiens 94-97 29960031-8 2018 In summary, XTT inhibited cell growth and induced apoptosis in HCC cells through ROS-mediated ERK/p38 MAPK activation and JAK2/STAT3 inhibition by GSH depletion. Reactive Oxygen Species 81-84 mitogen-activated protein kinase 1 Homo sapiens 102-106