PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29440177-4 2018 Ponatinib was tested for efficacy in two patient-derived xenograft (PDX) models and one cell-line xenograft model of SCCOHT.Results: The receptor tyrosine kinase (RTK) family was enriched in siRNA screen hits, with FGFRs and PDGFRs being overlapping hits between drug and siRNA screens. ponatinib 0-9 ret proto-oncogene Homo sapiens 137-161 29440177-4 2018 Ponatinib was tested for efficacy in two patient-derived xenograft (PDX) models and one cell-line xenograft model of SCCOHT.Results: The receptor tyrosine kinase (RTK) family was enriched in siRNA screen hits, with FGFRs and PDGFRs being overlapping hits between drug and siRNA screens. ponatinib 0-9 ret proto-oncogene Homo sapiens 163-166 29440177-6 2018 We further identified ponatinib as the most effective clinically approved RTK inhibitor. ponatinib 22-31 ret proto-oncogene Homo sapiens 74-77