PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29381821-4 2018 It remains unknown whether the cardioprotective effects of ticagrelor are also mediated by modulating myocardial galectin-3 expression. Ticagrelor 59-69 galectin 3 Rattus norvegicus 113-123 29381821-7 2018 RESULTS: Our results showed that ticagrelor treatment significantly reduced IA/AAR ratio at 3 and 7 days post I/R, downregulated mRNA and protein expression of galectin-3, as well as mRNA expression of TNF-alpha and IL-6 in infarct area at 24 h, 3 and 7 days post I/R. Ticagrelor 33-43 galectin 3 Rattus norvegicus 160-170 29381821-8 2018 CONCLUSIONS: Our results suggest that the cardioprotective effects of ticagrelor might partly be mediated by downregulating galectin-3 expression in infarct area in this rat model of myocardial I/R injury. Ticagrelor 70-80 galectin 3 Rattus norvegicus 124-134