PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29241092-4 2018 In this study, we showed that trehalose not only promoted autophagy, but also increased p62 protein expression, in an autophagy-independent manner. Trehalose 30-39 nucleoporin 62 Homo sapiens 88-91 29241092-5 2018 In addition, trehalose increased nuclear translocation of nuclear factor (erythroid-derived 2)-like 2 (Nrf2) in a p62-dependent manner and enhance expression of its downstream antioxidant factors, heme oxygenase-1 (Ho-1) and nicotinamide adenine dinucleotide phosphate quinone dehydrogenase 1 (Nqo1). Trehalose 13-22 nucleoporin 62 Homo sapiens 114-117 29241092-7 2018 Collectively, these results suggested that trehalose can function as a novel activator of the p62-Keap1/Nrf2 pathway, in addition to inducing autophagy. Trehalose 43-52 nucleoporin 62 Homo sapiens 94-97