PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29207042-0 2018 Anti-inflammatory effect of lovastatin is mediated via the modulation of NF-kappaB and inhibition of HDAC1 and the PI3K/Akt/mTOR pathway in RAW264.7 macrophages. Lovastatin 28-38 thymoma viral proto-oncogene 1 Mus musculus 120-123 29207042-12 2018 Therefore, the present study demonstrates that lovastatin inhibits the expression of pro-inflammatory mediators, including iNOS and TNF-alpha, through the suppression of HDAC1 expression, PI3K/Akt phosphorylation and NF-kappaB translocation in LPS-stimulated RAW264.7 macrophage cells. Lovastatin 47-57 thymoma viral proto-oncogene 1 Mus musculus 193-196