PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28963468-1	2017	Leucyl-tRNA synthetase (LRS) is known to function as leucine sensor in the mammalian target of rapamycin complex 1 (mTORC1) pathway.	Leucine	53-60	CREB regulated transcription coactivator 1	Mus musculus	116-122	
28963468-3	2017	Here, we demonstrate that the leucine sensor function for mTORC1 activation of LRS can be decoupled from its catalytic activity.	Leucine	30-37	CREB regulated transcription coactivator 1	Mus musculus	58-64	
28963468-7	2017	These findings suggest new strategies for controlling tumor growth that avoid the resistance to existing mTOR inhibitors resulting from cancer-associated MTOR mutations.Leucyl-tRNA synthetase (LRS) is a leucine sensor of the mTORC1 pathway.	Leucine	203-210	CREB regulated transcription coactivator 1	Mus musculus	225-231	
28963468-8	2017	Here, the authors identify inhibitors of the GTPase activating function of LRS, not affecting its catalytic activity, and demonstrate that the leucine sensor function of LRS can be a new target for mTORC1 inhibition.	Leucine	143-150	CREB regulated transcription coactivator 1	Mus musculus	198-204