PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28928082-0 2017 miR-338-3p confers 5-fluorouracil resistance in p53 mutant colon cancer cells by targeting the mammalian target of rapamycin. Fluorouracil 19-33 tumor protein p53 Homo sapiens 48-51 28928082-1 2017 Evidence demonstrate that p53 mutations and microRNAs (miRs) are important components of 5-FU resistance in colorectal cancer (CRC). Fluorouracil 89-93 tumor protein p53 Homo sapiens 26-29 28928082-8 2017 Moreover, inhibition of miR-338-3p in HT29 and HCT116 p53-/- cells increased their sensitivity to 5-FU treatment. Fluorouracil 98-102 tumor protein p53 Homo sapiens 54-57 28928082-10 2017 Our results reveal a critical and novel role of miR-338-3p in the correlation of 5-FU resistance with p53 status. Fluorouracil 81-85 tumor protein p53 Homo sapiens 102-105 28928082-11 2017 Moreover, the miR-338-3p inhibitor has the potential to overcome 5-FU resistance in p53 mutant colon cancer cells. Fluorouracil 65-69 tumor protein p53 Homo sapiens 84-87