PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28870911-7 2017 Mechanistically, blocking of de novo RNA synthesis by actinomycin D significantly inhibited sunitinib-induced expression of p53 mRNA, but not that of caspase-3, indicating involvement of a transcriptional mechanism. Dactinomycin 54-67 tumor protein p53 Homo sapiens 124-127