PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28804558-0 2017 NADPH oxidase 2 inhibitor diphenyleneiodonium enhances ROS-independent bacterial phagocytosis in murine macrophages via activation of the calcium-mediated p38 MAPK signaling pathway. diphenyleneiodonium 26-45 cytochrome b-245, beta polypeptide Mus musculus 0-15 28804558-3 2017 Here, we found that the classic NOX2 inhibitor diphenyleneiodonium (DPI) induced uptake of E. coli by murine peritoneal macrophages through enhancing phagocytosis, and this effect was temperature-sensitive and attenuated by cytochalasin D as well as chemical inhibition of Syk and PLCgamma, two downstream kinases involved in actin polymerization during phagocytosis. diphenyleneiodonium 47-66 cytochrome b-245, beta polypeptide Mus musculus 32-36 28804558-3 2017 Here, we found that the classic NOX2 inhibitor diphenyleneiodonium (DPI) induced uptake of E. coli by murine peritoneal macrophages through enhancing phagocytosis, and this effect was temperature-sensitive and attenuated by cytochalasin D as well as chemical inhibition of Syk and PLCgamma, two downstream kinases involved in actin polymerization during phagocytosis. diphenyleneiodonium 68-71 cytochrome b-245, beta polypeptide Mus musculus 32-36 28804558-5 2017 The DPI-induced enhancement of phagocytosis was independent of NOX2 inhibition or ROS generation but depended on increased intracellular calcium and activation of the p38 MAPK signaling pathway. diphenyleneiodonium 4-7 cytochrome b-245, beta polypeptide Mus musculus 63-67