PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28785380-0	2017	Ginkgolide B Suppresses TLR4-Mediated Inflammatory Response by Inhibiting the Phosphorylation of JAK2/STAT3 and p38 MAPK in High Glucose-Treated HUVECs.	ginkgolide B	0-12	toll like receptor 4	Homo sapiens	24-28	
28785380-0	2017	Ginkgolide B Suppresses TLR4-Mediated Inflammatory Response by Inhibiting the Phosphorylation of JAK2/STAT3 and p38 MAPK in High Glucose-Treated HUVECs.	ginkgolide B	0-12	Janus kinase 2	Homo sapiens	97-101	
28785380-0	2017	Ginkgolide B Suppresses TLR4-Mediated Inflammatory Response by Inhibiting the Phosphorylation of JAK2/STAT3 and p38 MAPK in High Glucose-Treated HUVECs.	ginkgolide B	0-12	signal transducer and activator of transcription 3	Homo sapiens	102-107	
28785380-0	2017	Ginkgolide B Suppresses TLR4-Mediated Inflammatory Response by Inhibiting the Phosphorylation of JAK2/STAT3 and p38 MAPK in High Glucose-Treated HUVECs.	ginkgolide B	0-12	mitogen-activated protein kinase 14	Homo sapiens	112-115	
28785380-0	2017	Ginkgolide B Suppresses TLR4-Mediated Inflammatory Response by Inhibiting the Phosphorylation of JAK2/STAT3 and p38 MAPK in High Glucose-Treated HUVECs.	Glucose	129-136	toll like receptor 4	Homo sapiens	24-28	
28785380-0	2017	Ginkgolide B Suppresses TLR4-Mediated Inflammatory Response by Inhibiting the Phosphorylation of JAK2/STAT3 and p38 MAPK in High Glucose-Treated HUVECs.	Glucose	129-136	Janus kinase 2	Homo sapiens	97-101	
28785380-0	2017	Ginkgolide B Suppresses TLR4-Mediated Inflammatory Response by Inhibiting the Phosphorylation of JAK2/STAT3 and p38 MAPK in High Glucose-Treated HUVECs.	Glucose	129-136	signal transducer and activator of transcription 3	Homo sapiens	102-107	
28785380-0	2017	Ginkgolide B Suppresses TLR4-Mediated Inflammatory Response by Inhibiting the Phosphorylation of JAK2/STAT3 and p38 MAPK in High Glucose-Treated HUVECs.	Glucose	129-136	mitogen-activated protein kinase 14	Homo sapiens	112-115	
28785380-1	2017	AIM: Ginkgolide B is a Ginkgo biloba leaf extract that has been identified as a natural platelet-activating factor receptor (PAFR) antagonist.	ginkgolide B	5-17	platelet activating factor receptor	Homo sapiens	125-129	
28785380-2	2017	We investigated the effect of ginkgolide B on high glucose-induced TLR4 activation in human umbilical vein endothelial cells (HUVECs).	ginkgolide B	30-42	toll like receptor 4	Homo sapiens	67-71	
28785380-2	2017	We investigated the effect of ginkgolide B on high glucose-induced TLR4 activation in human umbilical vein endothelial cells (HUVECs).	Glucose	51-58	toll like receptor 4	Homo sapiens	67-71	
28785380-5	2017	RESULTS: Ginkgolide B suppressed the expression of TLR4 and MyD88 that was induced by high glucose.	ginkgolide B	9-21	toll like receptor 4	Homo sapiens	51-55	
28785380-5	2017	RESULTS: Ginkgolide B suppressed the expression of TLR4 and MyD88 that was induced by high glucose.	ginkgolide B	9-21	MYD88 innate immune signal transduction adaptor	Homo sapiens	60-65	
28785380-5	2017	RESULTS: Ginkgolide B suppressed the expression of TLR4 and MyD88 that was induced by high glucose.	Glucose	91-98	toll like receptor 4	Homo sapiens	51-55	
28785380-5	2017	RESULTS: Ginkgolide B suppressed the expression of TLR4 and MyD88 that was induced by high glucose.	Glucose	91-98	MYD88 innate immune signal transduction adaptor	Homo sapiens	60-65	
28785380-6	2017	Ginkgolide B also reduced the levels of platelet endothelial cell adhesion molecule-1, interleukin-6, and monocyte chemotactic protein 1.	ginkgolide B	0-12	platelet and endothelial cell adhesion molecule 1	Homo sapiens	40-85	
28785380-6	2017	Ginkgolide B also reduced the levels of platelet endothelial cell adhesion molecule-1, interleukin-6, and monocyte chemotactic protein 1.	ginkgolide B	0-12	interleukin 6	Homo sapiens	87-100	
28785380-6	2017	Ginkgolide B also reduced the levels of platelet endothelial cell adhesion molecule-1, interleukin-6, and monocyte chemotactic protein 1.	ginkgolide B	0-12	C-C motif chemokine ligand 2	Homo sapiens	106-136	
28785380-8	2017	The result showed that high glucose treatment caused the binding of PAFR and TLR4, whereas ginkgolide B abolished this binding.	Glucose	28-35	platelet activating factor receptor	Homo sapiens	68-72	
28785380-8	2017	The result showed that high glucose treatment caused the binding of PAFR and TLR4, whereas ginkgolide B abolished this binding.	Glucose	28-35	toll like receptor 4	Homo sapiens	77-81	
28785380-9	2017	The functional analysis indicated that PAFR siRNA treatment reduced TLR4 expression, and TLR4 siRNA treatment decreased PAFR expression in high glucose-treated HUVECs, further supporting the coimmunoprecipitation data.	Glucose	144-151	toll like receptor 4	Homo sapiens	89-93	
28785380-9	2017	The functional analysis indicated that PAFR siRNA treatment reduced TLR4 expression, and TLR4 siRNA treatment decreased PAFR expression in high glucose-treated HUVECs, further supporting the coimmunoprecipitation data.	Glucose	144-151	platelet activating factor receptor	Homo sapiens	120-124	
28785380-10	2017	Ginkgolide B inhibited the phosphorylation of Janus kinase 2 (JAK2)/signal transducer and activator of transcription 3 (STAT3) and p38 mitogen-activated protein kinase (MAPK).	ginkgolide B	0-12	Janus kinase 2	Homo sapiens	46-60	
28785380-10	2017	Ginkgolide B inhibited the phosphorylation of Janus kinase 2 (JAK2)/signal transducer and activator of transcription 3 (STAT3) and p38 mitogen-activated protein kinase (MAPK).	ginkgolide B	0-12	Janus kinase 2	Homo sapiens	62-66	
28785380-10	2017	Ginkgolide B inhibited the phosphorylation of Janus kinase 2 (JAK2)/signal transducer and activator of transcription 3 (STAT3) and p38 mitogen-activated protein kinase (MAPK).	ginkgolide B	0-12	signal transducer and activator of transcription 3	Homo sapiens	68-118	
28785380-10	2017	Ginkgolide B inhibited the phosphorylation of Janus kinase 2 (JAK2)/signal transducer and activator of transcription 3 (STAT3) and p38 mitogen-activated protein kinase (MAPK).	ginkgolide B	0-12	signal transducer and activator of transcription 3	Homo sapiens	120-125	
28785380-10	2017	Ginkgolide B inhibited the phosphorylation of Janus kinase 2 (JAK2)/signal transducer and activator of transcription 3 (STAT3) and p38 mitogen-activated protein kinase (MAPK).	ginkgolide B	0-12	mitogen-activated protein kinase 14	Homo sapiens	131-167	
28785380-11	2017	CONCLUSION: Ginkgolide B exerted protective effects by inhibiting the TLR4-mediated inflammatory response in high glucose-treated endothelial cells.	ginkgolide B	12-24	toll like receptor 4	Homo sapiens	70-74	
28785380-11	2017	CONCLUSION: Ginkgolide B exerted protective effects by inhibiting the TLR4-mediated inflammatory response in high glucose-treated endothelial cells.	Glucose	114-121	toll like receptor 4	Homo sapiens	70-74	
28785380-12	2017	The mechanism of action of ginkgolide B might be associated with inhibition of the JAK2/STAT3 and p38 MAPK phosphorylation.	ginkgolide B	27-39	Janus kinase 2	Homo sapiens	83-87	
28785380-12	2017	The mechanism of action of ginkgolide B might be associated with inhibition of the JAK2/STAT3 and p38 MAPK phosphorylation.	ginkgolide B	27-39	signal transducer and activator of transcription 3	Homo sapiens	88-93	
28785380-12	2017	The mechanism of action of ginkgolide B might be associated with inhibition of the JAK2/STAT3 and p38 MAPK phosphorylation.	ginkgolide B	27-39	mitogen-activated protein kinase 14	Homo sapiens	98-101