PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28665968-1 2017 SLC19A3 deficiency, also called thiamine metabolism dysfunction syndrome-2 (THMD2; OMIM 607483), is an autosomal recessive neurodegenerative disorder caused by mutations in SLC19A3, the gene encoding thiamine transporter 2. Thiamine 32-40 solute carrier family 19 member 3 Homo sapiens 76-81 28665968-4 2017 These findings may bear some features of thiamine-deficient mice generated by pyrithiamine injection and a thiamine-deficient diet, suggesting that the primary cause of THMD2 could be thiamine pyrophosphate (TPP) deficiency. Thiamine 41-49 solute carrier family 19 member 3 Homo sapiens 169-174 28665968-9 2017 These results showed that acute neurodegeneration caused by thiamine deficiency is preventable in most parts, and prompt high-dose thiamine administration is critical for the treatment of THMD2. Thiamine 131-139 solute carrier family 19 member 3 Homo sapiens 188-193