PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28450110-0	2017	A hydrocortisone derivative binds to GAPDH and reduces the toxicity of extracellular polyglutamine-containing aggregates.	polyglutamine	85-98	glyceraldehyde-3-phosphate dehydrogenase	Rattus norvegicus	37-42	
28450110-4	2017	Here, we show that RX624, a derivative of hydrocortisone that binds to GAPDH, prevents the formation of aggregates of GAPDH-polyglutamine excreted into the culture medium by PC-12 rat cells expressing mutant huntingtin.	polyglutamine	124-137	glyceraldehyde-3-phosphate dehydrogenase	Rattus norvegicus	71-76	
28450110-4	2017	Here, we show that RX624, a derivative of hydrocortisone that binds to GAPDH, prevents the formation of aggregates of GAPDH-polyglutamine excreted into the culture medium by PC-12 rat cells expressing mutant huntingtin.	polyglutamine	124-137	glyceraldehyde-3-phosphate dehydrogenase	Rattus norvegicus	118-123	
28450110-5	2017	RX624 was previously shown to be unable to penetrate cells and, thus, its principal therapeutic action might be the inhibition of polyglutamine-GAPDH complex aggregation in the extracellular matrix.	polyglutamine	130-143	glyceraldehyde-3-phosphate dehydrogenase	Rattus norvegicus	144-149