PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28404639-7 2017 When HepG2 cells were exposed to LDL cholesterol, they developed cholesterol crystals in LD membranes, which caused activation of THP1 cells (macrophages) grown in coculture; upregulation of TNF-alpha, NLRP3, and interleukin 1beta (IL1beta) mRNA; and secretion of IL-1beta. Cholesterol 37-48 NLR family pyrin domain containing 3 Homo sapiens 202-207 28404639-7 2017 When HepG2 cells were exposed to LDL cholesterol, they developed cholesterol crystals in LD membranes, which caused activation of THP1 cells (macrophages) grown in coculture; upregulation of TNF-alpha, NLRP3, and interleukin 1beta (IL1beta) mRNA; and secretion of IL-1beta. Cholesterol 65-76 NLR family pyrin domain containing 3 Homo sapiens 202-207