PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28291036-7 2017 Formation of N-desmethylclozapine is correlated with activity of the cytochrome P450 enzymes 1A2 and 3A4 (CYP1A2 and CYP3A4). norclozapine 13-33 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 106-112 28291036-11 2017 Moreover, induction of CYP1A2, especially by omeprazole and lansoprazole, may increase the serum concentration of N-desmethylclozapine, which can accumulate in lymphocytes and may achieve toxic levels. norclozapine 114-134 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 23-29