PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
2801921-1	1989	Previous studies determined that direct activation of protein kinase C (PKC) with phorbol esters increases the number of angiotensin II (ANG II)-specific binding sites in neuronal cultures prepared from the hypothalamus and brain stem of 1-day-old rats.	Phorbol Esters	82-96	angiotensinogen	Rattus norvegicus	121-135	
2801921-1	1989	Previous studies determined that direct activation of protein kinase C (PKC) with phorbol esters increases the number of angiotensin II (ANG II)-specific binding sites in neuronal cultures prepared from the hypothalamus and brain stem of 1-day-old rats.	Phorbol Esters	82-96	angiotensinogen	Rattus norvegicus	137-143	
2801921-3	1989	In the present study we have examined whether stimulation of IP hydrolysis, and presumably activation of PKC, can mimic the actions of phorbol esters on ANG II-specific binding.	Phorbol Esters	135-149	angiotensinogen	Rattus norvegicus	153-159	
2801921-5	1989	Incubation of neuronal cultures with norepinephrine (NE) at concentrations (greater than 5 microM) and for times (15-60 min) that cause large increases in IP hydrolysis caused increases in the number of ANG II-specific binding sites, mimicking the actions of phorbol esters.	Phorbol Esters	259-273	angiotensinogen	Rattus norvegicus	203-209