PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27872312-3 2016 Here, we describe an innovative approach for targeting mast cells in vitro and in vivo using antisense oligonucleotide-mediated exon skipping of the beta-subunit of the high-affinity IgE receptor (FcepsilonRIbeta) to eliminate surface high-affinity IgE receptor (FcepsilonRI) expression and function, rendering mast cells unresponsive to IgE-mediated activation. Oligonucleotides 103-118 Fc epsilon receptor Ia Homo sapiens 197-208