PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27720690-0 2016 Aluminum trichloride induces bone impairment through TGF-beta1/Smad signaling pathway. Aluminum Chloride 0-20 SMAD family member 4 Rattus norvegicus 63-67 27720690-6 2016 Moreover, we found exogenous TGF-beta1 application reversed the inhibitory effect of AlCl3 on osteoblasts activity by activating the TGF-beta1/Smad signaling pathway and increasing the mRNA expressions of ALP and Col I in osteoblasts. Aluminum Chloride 85-90 SMAD family member 4 Rattus norvegicus 143-147 27720690-7 2016 These results demonstrate that AlCl3 induces bone impairment through inactivation of TGF-beta1/Smad signaling pathway. Aluminum Chloride 31-36 SMAD family member 4 Rattus norvegicus 95-99