PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27704398-6 2017 Genetic testing revealed the presence of a heterozygous variant of unknown significance (VUS) in the cysteine-rich region of exon 10 in the RET gene (c.1846G>C, p.E616Q), in both affected siblings and their unaffected mother. Cysteine 101-109 ret proto-oncogene Homo sapiens 140-143 27704398-8 2017 Variants in the cysteine-rich region of the RET gene, outside of the key cysteine residues, may contribute to the development of MEN2 in a less aggressive manner, with a lower penetrance of MTC. Cysteine 16-24 ret proto-oncogene Homo sapiens 44-47 27704398-8 2017 Variants in the cysteine-rich region of the RET gene, outside of the key cysteine residues, may contribute to the development of MEN2 in a less aggressive manner, with a lower penetrance of MTC. Cysteine 73-81 ret proto-oncogene Homo sapiens 44-47