PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27650274-7 2016 FcepsilonRI cell surface expression, FcepsilonRIalpha-specific mRNA and FcepsilonRI-mediated histamine release are all augmented by IL-4, while histamine release elicited by the non-immunological stimulus, substance P, remains unaffected. Histamine 93-102 Fc epsilon receptor Ia Homo sapiens 37-83 27650274-7 2016 FcepsilonRI cell surface expression, FcepsilonRIalpha-specific mRNA and FcepsilonRI-mediated histamine release are all augmented by IL-4, while histamine release elicited by the non-immunological stimulus, substance P, remains unaffected. Histamine 93-102 interleukin 4 Homo sapiens 132-136 27650274-9 2016 Intriguingly, IL-4 impacts granule-associated mediators, especially histamine whose synthesis is boosted in the presence of IL-4. Histamine 68-77 interleukin 4 Homo sapiens 14-18 27650274-9 2016 Intriguingly, IL-4 impacts granule-associated mediators, especially histamine whose synthesis is boosted in the presence of IL-4. Histamine 68-77 interleukin 4 Homo sapiens 124-128 27650274-10 2016 To our knowledge, an increase in histamine production by IL-4 has not been described yet for any type of MCs, but may well contribute to its pro-allergic effect given the significance of this biogenic amine to allergic symptoms. Histamine 33-42 interleukin 4 Homo sapiens 57-61 27650274-10 2016 To our knowledge, an increase in histamine production by IL-4 has not been described yet for any type of MCs, but may well contribute to its pro-allergic effect given the significance of this biogenic amine to allergic symptoms. Amines 37-42 interleukin 4 Homo sapiens 57-61