PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2760844-2 1989 Release was monitored by measuring endogenous ACh when acetylcholinesterase (AChE) was inhibited with physostigmine (30 microM) or by measuring endogenous choline when AChE activity was left intact. Acetylcholine 46-49 acetylcholinesterase Rattus norvegicus 77-81 2760844-2 1989 Release was monitored by measuring endogenous ACh when acetylcholinesterase (AChE) was inhibited with physostigmine (30 microM) or by measuring endogenous choline when AChE activity was left intact. Physostigmine 102-115 acetylcholinesterase Rattus norvegicus 55-75 2760844-2 1989 Release was monitored by measuring endogenous ACh when acetylcholinesterase (AChE) was inhibited with physostigmine (30 microM) or by measuring endogenous choline when AChE activity was left intact. Physostigmine 102-115 acetylcholinesterase Rattus norvegicus 77-81 2760844-2 1989 Release was monitored by measuring endogenous ACh when acetylcholinesterase (AChE) was inhibited with physostigmine (30 microM) or by measuring endogenous choline when AChE activity was left intact. Choline 61-68 acetylcholinesterase Rattus norvegicus 77-81 2760844-3 1989 The classical antagonist, atropine (0.1-2 microM), induced an increase in release whether AChE activity was inhibited or intact. Atropine 26-34 acetylcholinesterase Rattus norvegicus 90-94 2760844-4 1989 The putative M-1 selective antagonist, pirenzepine, had minimal effects over a broad concentration range (2-200 microM) and induced an increase in ACh release only when AChE activity was inhibited. Pirenzepine 39-50 acetylcholinesterase Rattus norvegicus 169-173 2760844-5 1989 The classical agonist, oxotremorine (10-100 microM) decreased effectively ACh release (by 22-35%), but only when AChE activity was intact. Oxotremorine 23-35 acetylcholinesterase Rattus norvegicus 113-117 2760844-6 1989 The oxotremorine analog, oxotremorine-M, was apparently more potent than oxotremorine, but also decreased ACh release (by 24-41%) only when AChE activity was intact. Oxotremorine 4-16 acetylcholinesterase Rattus norvegicus 140-144 2760844-6 1989 The oxotremorine analog, oxotremorine-M, was apparently more potent than oxotremorine, but also decreased ACh release (by 24-41%) only when AChE activity was intact. Oxotremorine 25-37 acetylcholinesterase Rattus norvegicus 140-144 2760844-6 1989 The oxotremorine analog, oxotremorine-M, was apparently more potent than oxotremorine, but also decreased ACh release (by 24-41%) only when AChE activity was intact. Oxotremorine 25-37 acetylcholinesterase Rattus norvegicus 140-144 2760844-7 1989 Another oxotremorine analog, BM-5, behaved more like a muscarinic antagonist in its effects on neostriatal ACh release, and the highest concentration tested (100 microM) increased release (by 47%) when AChE activity was left intact. Oxotremorine 8-20 acetylcholinesterase Rattus norvegicus 202-206 2760844-7 1989 Another oxotremorine analog, BM-5, behaved more like a muscarinic antagonist in its effects on neostriatal ACh release, and the highest concentration tested (100 microM) increased release (by 47%) when AChE activity was left intact. N-methyl-N-(1-methyl-4-pyrrolidino-2-butynyl)acetamide 29-33 acetylcholinesterase Rattus norvegicus 202-206