PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27580186-0 2016 Design, synthesis and biological evaluation of dihydroquinoxalinone derivatives as BRD4 inhibitors. dihydroquinoxalinone 47-67 bromodomain containing 4 Homo sapiens 83-87 27580186-3 2016 In this study, we synthesized a series of dihydroquinoxalinone derivatives and evaluated their BRD4 inhibitory activities, obtaining compound 5i with IC50 value of 73nM of binding activity in BRD4(1) and 258nM of cellular activity in MV-4-11 cancer cell lines. dihydroquinoxalinone 42-62 bromodomain containing 4 Homo sapiens 95-99 27580186-3 2016 In this study, we synthesized a series of dihydroquinoxalinone derivatives and evaluated their BRD4 inhibitory activities, obtaining compound 5i with IC50 value of 73nM of binding activity in BRD4(1) and 258nM of cellular activity in MV-4-11 cancer cell lines. dihydroquinoxalinone 42-62 bromodomain containing 4 Homo sapiens 192-196