PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27324742-3 2016 METHODS: A series of 3-arylidene-5-(naphthalene-2-yl)-furan-2(3H)-ones (2a-j) were synthesized by incorporating pharmacophore of COX-2 inhibitor rofecoxib and naphthyl ring of naproxen as potential non steroidal anti-inflammatory agents. rofecoxib 145-154 mitochondrially encoded cytochrome c oxidase II Homo sapiens 129-134