PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27233942-5 2016 Stronger intracellular TrxR inhibition and higher accumulation of ROS (O2( -) and H2O2) are responsible for more effective S-phase arrest and mitochondria-mediated apoptotic induction of A549 cells by PL-CL than PLvia p53-p21-cyclinA/CDK2 and ASK1-JNK/p38 signaling cascade pathways, respectively. Reactive Oxygen Species 66-69 tumor protein p53 Homo sapiens 218-221