PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26983878-8 2016 BETi preferentially target super-enhancer-regulated genes, and a super-enhancer in c-MYC was recently identified in HCT116 cells to which BRD4 and effector transcription factors of the WNT/beta-catenin/TCF and MEK/ERK pathways are recruited. beti 0-4 bromodomain containing 4 Homo sapiens 138-142 26983878-8 2016 BETi preferentially target super-enhancer-regulated genes, and a super-enhancer in c-MYC was recently identified in HCT116 cells to which BRD4 and effector transcription factors of the WNT/beta-catenin/TCF and MEK/ERK pathways are recruited. beti 0-4 catenin beta 1 Homo sapiens 189-201 26983878-8 2016 BETi preferentially target super-enhancer-regulated genes, and a super-enhancer in c-MYC was recently identified in HCT116 cells to which BRD4 and effector transcription factors of the WNT/beta-catenin/TCF and MEK/ERK pathways are recruited. beti 0-4 hepatocyte nuclear factor 4 alpha Homo sapiens 202-205 26983878-8 2016 BETi preferentially target super-enhancer-regulated genes, and a super-enhancer in c-MYC was recently identified in HCT116 cells to which BRD4 and effector transcription factors of the WNT/beta-catenin/TCF and MEK/ERK pathways are recruited. beti 0-4 mitogen-activated protein kinase kinase 7 Homo sapiens 210-213 26983878-8 2016 BETi preferentially target super-enhancer-regulated genes, and a super-enhancer in c-MYC was recently identified in HCT116 cells to which BRD4 and effector transcription factors of the WNT/beta-catenin/TCF and MEK/ERK pathways are recruited. beti 0-4 mitogen-activated protein kinase 1 Homo sapiens 214-217 26983878-10 2016 These findings demonstrate that BETi downregulate c-MYC expression and inhibit colorectal cancer cell proliferation and identify strategies for enhancing the effects of BETi on c-MYC repression by combinatorial targeting the c-MYC super-enhancer. beti 32-36 MYC proto-oncogene, bHLH transcription factor Homo sapiens 50-55 26983878-10 2016 These findings demonstrate that BETi downregulate c-MYC expression and inhibit colorectal cancer cell proliferation and identify strategies for enhancing the effects of BETi on c-MYC repression by combinatorial targeting the c-MYC super-enhancer. beti 169-173 MYC proto-oncogene, bHLH transcription factor Homo sapiens 177-182 26983878-10 2016 These findings demonstrate that BETi downregulate c-MYC expression and inhibit colorectal cancer cell proliferation and identify strategies for enhancing the effects of BETi on c-MYC repression by combinatorial targeting the c-MYC super-enhancer. beti 169-173 MYC proto-oncogene, bHLH transcription factor Homo sapiens 177-182