PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26965143-5 2016 Specifically, either inhibition of ATM with caffeine or mutation of p53 (serine 15 to alanine) restored MDM2-dependent polyubiquitination of otherwise monoubiquitinated mutant p53. Caffeine 44-52 tumor protein p53 Homo sapiens 176-179 26965143-6 2016 Caffeine treatment rescued MDM2-dependent proteasome degradation of mutant p53 in cells exhibiting active DNA damage signaling, and ATM knockdown phenocopied the caffeine effect. Caffeine 0-8 tumor protein p53 Homo sapiens 75-78