PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26541454-2 2015 The amounts of MGL_1304 and IgE against MGL_1304 are evaluated by the histamine release test using basophils or mast cells sensitized with serum containing IgE against MGL_1304, and enzyme linked sorbent assay (ELISA) using MGL_1304 and anti-MGL_1304 antibodies. Histamine 70-79 immunoglobulin heavy constant epsilon Homo sapiens 28-31 26541454-3 2015 Here, we identified a human monoclonal IgE (ABS-IgE) that binds to the high affinity IgE receptor (FcepsilonRI) and MGL_1304 with high affinity (KD = 1.99 nM) but does not release histamine from basophils and mast cells. Histamine 180-189 immunoglobulin heavy constant epsilon Homo sapiens 39-42 26541454-3 2015 Here, we identified a human monoclonal IgE (ABS-IgE) that binds to the high affinity IgE receptor (FcepsilonRI) and MGL_1304 with high affinity (KD = 1.99 nM) but does not release histamine from basophils and mast cells. Histamine 180-189 immunoglobulin heavy constant epsilon Homo sapiens 48-51 26541454-6 2015 Moreover, ABS-IgE prevented histamine release from mast cells and basophils by neutralizing MGL_1304 not only in a free form in solution, but also on FcepsilonRI expressed on the cell surface without cell activation. Histamine 28-37 immunoglobulin heavy constant epsilon Homo sapiens 10-17