PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26497555-4 2015 Here, we show that at moderate levels of ROS, Sp1 directly binds to two GC boxes within the ZNF32 promoter to activate ZNF32 transcription. Reactive Oxygen Species 41-44 zinc finger protein 32 Homo sapiens 92-97 26497555-4 2015 Here, we show that at moderate levels of ROS, Sp1 directly binds to two GC boxes within the ZNF32 promoter to activate ZNF32 transcription. Reactive Oxygen Species 41-44 zinc finger protein 32 Homo sapiens 119-124 26497555-5 2015 Alternatively, at cytotoxic ROS concentrations, ZNF32 expression is repressed due to decreased binding activity of Sp1. Reactive Oxygen Species 28-31 zinc finger protein 32 Homo sapiens 48-53 26497555-6 2015 ZNF32 overexpression maintains mitochondrial membrane potential and enhances the antioxidant capacity of cells to detoxify ROS, and these effects promote cell survival upon pro-oxidant agent treatment. Reactive Oxygen Species 123-126 zinc finger protein 32 Homo sapiens 0-5