PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26471256-3 2016 Clinical studies also suggest that abnormalities in cholinergic signaling are associated with major depressive disorder, whereas pre-clinical studies have implicated both beta2 subunit-containing (beta2*) and alpha7 nAChRs in the effects of nicotine in models of anxiety- and depression-like behaviors. Nicotine 241-249 cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus 209-215