PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26156677-4	2015	Using mutational analysis and computational study, we determine that Arg316 in RXRalpha, essential for 9-cis-retinoic acid binding and activating RXRalpha transactivation, is not required for antagonist effects of N-6, whereas Trp305 and Phe313 are crucial for N-6 binding to RXRalpha by forming extra pi-pi stacking interactions with N-6, indicating a distinct RXRalpha binding mode of N-6.	Alitretinoin	103-122	retinoid X receptor alpha	Homo sapiens	79-87