PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25963768-5 2015 Herein, we report for the first time that the hydrogen peroxide (H2O2), a redox signaling molecule, generated by these EHNs activates the endothelial nitric oxide synthase (eNOS) that promotes the nitric oxide (NO) production in a PI3K (phosphoinositide 3-kinase)/Akt dependent manner, eventually triggering angiogenesis. Hydrogen Peroxide 46-63 AKT serine/threonine kinase 1 Homo sapiens 264-267 25963768-5 2015 Herein, we report for the first time that the hydrogen peroxide (H2O2), a redox signaling molecule, generated by these EHNs activates the endothelial nitric oxide synthase (eNOS) that promotes the nitric oxide (NO) production in a PI3K (phosphoinositide 3-kinase)/Akt dependent manner, eventually triggering angiogenesis. Hydrogen Peroxide 65-69 AKT serine/threonine kinase 1 Homo sapiens 264-267