PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25921217-1 2015 Salpichrolides are natural plant steroids that contain an unusual six-membered aromatic ring D. We recently reported that some of these compounds, and certain analogs with a simplified side chain, exhibited antagonist effects toward the human estrogen receptor (ER), a nuclear receptor whose endogenous ligand has an aromatic A ring (estradiol). Steroids 33-41 estrogen receptor 1 Homo sapiens 243-260 25921217-1 2015 Salpichrolides are natural plant steroids that contain an unusual six-membered aromatic ring D. We recently reported that some of these compounds, and certain analogs with a simplified side chain, exhibited antagonist effects toward the human estrogen receptor (ER), a nuclear receptor whose endogenous ligand has an aromatic A ring (estradiol). Steroids 33-41 estrogen receptor 1 Homo sapiens 262-264