PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25823784-2 2015 PATIENTS & METHODS: Polymorphisms of the NADPH oxidase subunits and of the anthracycline transporters ABCC1, ABCC2 and SLC28A3 were genotyped in elderly patients (61-80 years) treated for aggressive CD20(+) B-cell lymphomas with CHOP-14 with or without rituximab and followed up for 3 years. Adenosine Monophosphate 10-13 ATP binding cassette subfamily C member 1 Homo sapiens 106-111 25823784-3 2015 RESULTS: The accumulation of RAC2 subunit genotypes TA/AA among cases was statistically significant upon adjustment for gender, age and doxorubicin dose in a multivariate logistic regression analysis (OR: 2.3, p = 0.028; univariate: OR: 1.8, p = 0.077). Doxorubicin 136-147 Rac family small GTPase 2 Homo sapiens 29-33 25823784-4 2015 RAC2 and CYBA genotypes were significantly associated with anthracycline-induced cardiotoxicity in a meta-analysis of this and a similar previous study. Anthracyclines 59-72 Rac family small GTPase 2 Homo sapiens 0-4 25823784-4 2015 RAC2 and CYBA genotypes were significantly associated with anthracycline-induced cardiotoxicity in a meta-analysis of this and a similar previous study. Anthracyclines 59-72 cytochrome b-245 alpha chain Homo sapiens 9-13