PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25707716-7 2015 RESULTS: In human dermal microvascular endothelial cells, endothelin 1 induced phosphorylation of Fli-1 at Thr(312) through the sequential activation of c-Abl and protein kinase Cdelta, leading to a decrease in Fli-1 protein levels as well as a decrease in binding of Fli-1 to the target gene promoters, whereas bosentan treatment reversed those effects. Bosentan 312-320 Fli-1 proto-oncogene, ETS transcription factor Homo sapiens 98-103