PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25695425-2 2015 The commercially available alkaloid boldine (2) was used as the starting material for synthesis of various C-9 alkoxy analogues of N-methyllaurotetanine in order to gauge the effect of C-9 alkylation on affinity and selectivity at 5-HT1A, 5-HT2A, and 5-HT7 receptors. Alkaloids 27-35 5-hydroxytryptamine receptor 2A Homo sapiens 241-245