PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25678016-0	2015	Discovery and structure-activity relationship studies of N6-benzoyladenine derivatives as novel BRD4 inhibitors.	N6-benzoyladenine	57-74	bromodomain containing 4	Homo sapiens	96-100	
25678016-3	2015	As a part of our continuing structural development studies of thalidomide to obtain a broad spectrum of biological modifiers based on the "multi-template" approach, in this work we focused on BRD4-inhibitory activity, and discovered that N6-benzoyladenine derivatives exhibit this activity.	N6-benzoyladenine	238-255	bromodomain containing 4	Homo sapiens	192-196	
25678016-4	2015	Structure-activity relationship studies led to N6-(2,4,5-trimethoxybenzoyl)adenine (29), which exhibits potent BRD4 bromodomain1 inhibitory activity with an IC50 value of 0.427muM.	n6-(2,4,5-trimethoxybenzoyl)adenine	47-82	bromodomain containing 4	Homo sapiens	111-115	
25678016-5	2015	N6-Benzoyladenine appears to be a new chemical scaffold for development of BRD4 inhibitors.	N6-benzoyladenine	0-17	bromodomain containing 4	Homo sapiens	75-79