PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25651569-2 2015 We investigated the role of soluble uric acid in NLRP3 inflammasome activation in macrophages to demonstrate the effect of systemic hyperuricemia on progressive kidney damage in type 2 diabetes. Uric Acid 36-45 NLR family pyrin domain containing 3 Homo sapiens 49-54 25651569-5 2015 Soluble uric acid stimulated NLRP3 inflammasomes to produce IL-1beta in macrophages. Uric Acid 8-17 NLR family pyrin domain containing 3 Homo sapiens 29-34 25651569-6 2015 Uric acid-induced MitoSOX mediates NLRP3 activation and IL-1beta secretion. Uric Acid 0-9 NLR family pyrin domain containing 3 Homo sapiens 35-40