PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25542083-6 2015 However, the most interesting observation was that both temozolomide and curcumin required ERK1/2 to induce autophagy. Curcumin 73-81 mitogen-activated protein kinase 3 Homo sapiens 91-97 25542083-7 2015 Blocking this ERK1/2-mediated temozolomide and curcumin induced autophagy with resveratrol, a blood-brain barrier permeable drug, improved temozolomide/curcumin efficacy in brain-implanted tumors. Curcumin 47-55 mitogen-activated protein kinase 3 Homo sapiens 14-20 25542083-7 2015 Blocking this ERK1/2-mediated temozolomide and curcumin induced autophagy with resveratrol, a blood-brain barrier permeable drug, improved temozolomide/curcumin efficacy in brain-implanted tumors. Curcumin 152-160 mitogen-activated protein kinase 3 Homo sapiens 14-20