PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2546796-0 1989 Potentiation by adrenaline of thrombin-induced elevation of pHi is not essential for synergistic activation of human platelets. Epinephrine 16-26 coagulation factor II, thrombin Homo sapiens 30-38 2546796-2 1989 Adrenaline markedly enhanced the thrombin-induced increase in cytoplasmic pH (pHi) in BCECF-loaded platelets. Epinephrine 0-10 coagulation factor II, thrombin Homo sapiens 33-41 2546796-4 1989 The potentiation by adrenaline of thrombin-induced PLC activation measured as [32P]PA formation and final platelet responses was, however, not blocked by EIPA, even at low concentrations of thrombin. Epinephrine 20-30 coagulation factor II, thrombin Homo sapiens 34-42 2546796-5 1989 These results indicate that the enhancement by adrenaline of thrombin-induced cytoplasmic alkalinization may be a secondary effect which is not essential for the potentiation by adrenaline of platelet activation by thrombin. Epinephrine 47-57 coagulation factor II, thrombin Homo sapiens 61-69