PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25373357-0	2015	Relationships between the antidotal efficacy and structure, PK/PD parameters and bio-relevant molecular descriptors of AChE reactivating oximes: inclusion and integration to biopharmaceutical classification systems.	Oximes	137-143	acetylcholinesterase (Cartwright blood group)	Homo sapiens	119-123	
25373357-1	2015	INTRODUCTION: The therapeutic outcome of oximes used as reactivators of phosphorylated human acetylcholinesterase (AChE) is influenced, among other factors, by their biological distribution, their in vivo ability to achieve the nucleophilic attack and their affinity for the anionic center of the intact/inhibited AChE.	Oximes	41-47	acetylcholinesterase (Cartwright blood group)	Homo sapiens	93-113	
25373357-1	2015	INTRODUCTION: The therapeutic outcome of oximes used as reactivators of phosphorylated human acetylcholinesterase (AChE) is influenced, among other factors, by their biological distribution, their in vivo ability to achieve the nucleophilic attack and their affinity for the anionic center of the intact/inhibited AChE.	Oximes	41-47	acetylcholinesterase (Cartwright blood group)	Homo sapiens	115-119	
25373357-1	2015	INTRODUCTION: The therapeutic outcome of oximes used as reactivators of phosphorylated human acetylcholinesterase (AChE) is influenced, among other factors, by their biological distribution, their in vivo ability to achieve the nucleophilic attack and their affinity for the anionic center of the intact/inhibited AChE.	Oximes	41-47	acetylcholinesterase (Cartwright blood group)	Homo sapiens	314-318	
25373357-5	2015	EXPERT OPINION: The structural differences of the organophosphorus compounds (OP) and the available oximes reactivators of OP-inhibited AChE generate distinct toxicokinetic or PK profiles.	Oximes	100-106	acetylcholinesterase (Cartwright blood group)	Homo sapiens	136-140