PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25338565-8	2014	It is concluded that GSK525762A can inhibit the proliferation of KU812 cells and induce cell apoptosis possibly through depressing the transcription of C-MYC, BCL-2, CDK6 and BCL-xL gene, and down-regulating BAK and BAX transcription.	molibresib	21-31	BCL2 antagonist/killer 1	Homo sapiens	208-211	
25338565-0	2014	[Effect of BRD4 inhibitor GSK525762A on proliferation and apoptosis of KU812 leukemic cells and its mechanism].	molibresib	26-36	bromodomain containing 4	Homo sapiens	11-15	
25338565-1	2014	This study was purposed to investigate the effect of bromodomain-containing protein 4 (BRD4) inhibitor GSK525762A on the proliferation and apoptosis of chronic myeloid leukemia blast crisis KU812 cells and its mechanism.	molibresib	103-113	bromodomain containing 4	Homo sapiens	53-85	
25338565-1	2014	This study was purposed to investigate the effect of bromodomain-containing protein 4 (BRD4) inhibitor GSK525762A on the proliferation and apoptosis of chronic myeloid leukemia blast crisis KU812 cells and its mechanism.	molibresib	103-113	bromodomain containing 4	Homo sapiens	87-91	
25338565-7	2014	After GSK525762A treatment, the mRNA levels of proliferation-promoting genes ( C-MYC and CDK6) and pro-survival genes ( BCL-2 and BCL-xL) decreased, while the transcription level of pro-apoptosis genes BAK and BAX increased, as compared to that of the control group.	molibresib	6-16	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	79-84	
25338565-7	2014	After GSK525762A treatment, the mRNA levels of proliferation-promoting genes ( C-MYC and CDK6) and pro-survival genes ( BCL-2 and BCL-xL) decreased, while the transcription level of pro-apoptosis genes BAK and BAX increased, as compared to that of the control group.	molibresib	6-16	cyclin dependent kinase 6	Homo sapiens	89-93	
25338565-7	2014	After GSK525762A treatment, the mRNA levels of proliferation-promoting genes ( C-MYC and CDK6) and pro-survival genes ( BCL-2 and BCL-xL) decreased, while the transcription level of pro-apoptosis genes BAK and BAX increased, as compared to that of the control group.	molibresib	6-16	BCL2 apoptosis regulator	Homo sapiens	120-125	
25338565-7	2014	After GSK525762A treatment, the mRNA levels of proliferation-promoting genes ( C-MYC and CDK6) and pro-survival genes ( BCL-2 and BCL-xL) decreased, while the transcription level of pro-apoptosis genes BAK and BAX increased, as compared to that of the control group.	molibresib	6-16	BCL2 like 1	Homo sapiens	130-136	
25338565-7	2014	After GSK525762A treatment, the mRNA levels of proliferation-promoting genes ( C-MYC and CDK6) and pro-survival genes ( BCL-2 and BCL-xL) decreased, while the transcription level of pro-apoptosis genes BAK and BAX increased, as compared to that of the control group.	molibresib	6-16	BCL2 antagonist/killer 1	Homo sapiens	202-205	
25338565-7	2014	After GSK525762A treatment, the mRNA levels of proliferation-promoting genes ( C-MYC and CDK6) and pro-survival genes ( BCL-2 and BCL-xL) decreased, while the transcription level of pro-apoptosis genes BAK and BAX increased, as compared to that of the control group.	molibresib	6-16	BCL2 associated X, apoptosis regulator	Homo sapiens	210-213	
25338565-8	2014	It is concluded that GSK525762A can inhibit the proliferation of KU812 cells and induce cell apoptosis possibly through depressing the transcription of C-MYC, BCL-2, CDK6 and BCL-xL gene, and down-regulating BAK and BAX transcription.	molibresib	21-31	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	152-157	
25338565-8	2014	It is concluded that GSK525762A can inhibit the proliferation of KU812 cells and induce cell apoptosis possibly through depressing the transcription of C-MYC, BCL-2, CDK6 and BCL-xL gene, and down-regulating BAK and BAX transcription.	molibresib	21-31	BCL2 apoptosis regulator	Homo sapiens	159-164	
25338565-8	2014	It is concluded that GSK525762A can inhibit the proliferation of KU812 cells and induce cell apoptosis possibly through depressing the transcription of C-MYC, BCL-2, CDK6 and BCL-xL gene, and down-regulating BAK and BAX transcription.	molibresib	21-31	cyclin dependent kinase 6	Homo sapiens	166-170	
25338565-8	2014	It is concluded that GSK525762A can inhibit the proliferation of KU812 cells and induce cell apoptosis possibly through depressing the transcription of C-MYC, BCL-2, CDK6 and BCL-xL gene, and down-regulating BAK and BAX transcription.	molibresib	21-31	BCL2 like 1	Homo sapiens	175-181	
25338565-8	2014	It is concluded that GSK525762A can inhibit the proliferation of KU812 cells and induce cell apoptosis possibly through depressing the transcription of C-MYC, BCL-2, CDK6 and BCL-xL gene, and down-regulating BAK and BAX transcription.	molibresib	21-31	BCL2 associated X, apoptosis regulator	Homo sapiens	216-219