PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25189390-4 2014 Moreover, we found that 17beta-estradiol protects osteocytes against apoptosis via the NO/cGMP signaling pathway: type II PKG mediates estradiol-induced activation of the prosurvival kinases Erk and Akt, whereas type I PKG contributes to prosurvival signaling by directly phosphorylating and inactivating the cell death protein BAD. Estradiol 24-40 mitogen-activated protein kinase 1 Homo sapiens 191-194 25189390-4 2014 Moreover, we found that 17beta-estradiol protects osteocytes against apoptosis via the NO/cGMP signaling pathway: type II PKG mediates estradiol-induced activation of the prosurvival kinases Erk and Akt, whereas type I PKG contributes to prosurvival signaling by directly phosphorylating and inactivating the cell death protein BAD. Estradiol 31-40 mitogen-activated protein kinase 1 Homo sapiens 191-194