PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25165814-8 2014 Only SIRT3 overexpression affected fatty acid metabolism, and only SIRT4 overexpression altered superoxide levels and mitochondrial membrane potential. Superoxides 96-106 sirtuin 4 Homo sapiens 67-72 25165814-10 2014 SIRT3, SIRT4, and SIRT5 appear to respond to excess glucose by inducing a coordinated increase of glycolysis and respiration, with the excess energy dissipated via proton leak. Glucose 52-59 sirtuin 3 Homo sapiens 0-5 25165814-10 2014 SIRT3, SIRT4, and SIRT5 appear to respond to excess glucose by inducing a coordinated increase of glycolysis and respiration, with the excess energy dissipated via proton leak. Glucose 52-59 sirtuin 4 Homo sapiens 7-12 25165814-10 2014 SIRT3, SIRT4, and SIRT5 appear to respond to excess glucose by inducing a coordinated increase of glycolysis and respiration, with the excess energy dissipated via proton leak. Glucose 52-59 sirtuin 5 Homo sapiens 18-23