PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25139423-0 2014 Polyglutamine-expanded ataxin-3 impairs long-term depression in Purkinje neurons of SCA3 transgenic mouse by inhibiting HAT and impairing histone acetylation. polyglutamine 0-13 ataxin 3 Mus musculus 23-31 25139423-0 2014 Polyglutamine-expanded ataxin-3 impairs long-term depression in Purkinje neurons of SCA3 transgenic mouse by inhibiting HAT and impairing histone acetylation. polyglutamine 0-13 ataxin 3 Mus musculus 84-88 25139423-8 2014 Our results suggest that polyglutamine-expanded ataxin-3-Q79 impairs HAT activity, leading to histone hypoacetylation, downregulated expression of cerebellar genes required for LTD induction and impaired induction of cerebellar LTD in the SCA3 transgenic mouse. polyglutamine 25-38 ataxin 3 Mus musculus 48-56 25139423-8 2014 Our results suggest that polyglutamine-expanded ataxin-3-Q79 impairs HAT activity, leading to histone hypoacetylation, downregulated expression of cerebellar genes required for LTD induction and impaired induction of cerebellar LTD in the SCA3 transgenic mouse. polyglutamine 25-38 ataxin 3 Mus musculus 239-243