PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25091930-3 2014 The potency of the carboxylate series is now further improved through structure-based optimization of ligand-protein interactions in the proline binding site which exploits the H-bond interactions necessary for Pin1 catalytic function. Proline 137-144 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 Homo sapiens 211-215