PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24769339-0 2014 Polyunsaturated fatty acids inhibit stimulated coupling between the ER Ca(2+) sensor STIM1 and the Ca(2+) channel protein Orai1 in a process that correlates with inhibition of stimulated STIM1 oligomerization. Fatty Acids, Unsaturated 0-27 stromal interaction molecule 1 Homo sapiens 85-90 24769339-0 2014 Polyunsaturated fatty acids inhibit stimulated coupling between the ER Ca(2+) sensor STIM1 and the Ca(2+) channel protein Orai1 in a process that correlates with inhibition of stimulated STIM1 oligomerization. Fatty Acids, Unsaturated 0-27 ORAI calcium release-activated calcium modulator 1 Homo sapiens 122-127 24769339-0 2014 Polyunsaturated fatty acids inhibit stimulated coupling between the ER Ca(2+) sensor STIM1 and the Ca(2+) channel protein Orai1 in a process that correlates with inhibition of stimulated STIM1 oligomerization. Fatty Acids, Unsaturated 0-27 stromal interaction molecule 1 Homo sapiens 187-192 24769339-1 2014 Polyunsaturated fatty acids (PUFAs) have been found to be effective inhibitors of cell signaling in numerous contexts, and we find that acute addition of micromolar PUFAs such as linoleic acid effectively inhibit of Ca(2+) responses in mast cells stimulated by antigen-mediated crosslinking of FcepsilonRI or by the SERCA pump inhibitor, thapsigargin. Fatty Acids, Unsaturated 0-27 Fc epsilon receptor Ia Homo sapiens 294-305 24769339-1 2014 Polyunsaturated fatty acids (PUFAs) have been found to be effective inhibitors of cell signaling in numerous contexts, and we find that acute addition of micromolar PUFAs such as linoleic acid effectively inhibit of Ca(2+) responses in mast cells stimulated by antigen-mediated crosslinking of FcepsilonRI or by the SERCA pump inhibitor, thapsigargin. Fatty Acids, Unsaturated 29-34 Fc epsilon receptor Ia Homo sapiens 294-305 24769339-1 2014 Polyunsaturated fatty acids (PUFAs) have been found to be effective inhibitors of cell signaling in numerous contexts, and we find that acute addition of micromolar PUFAs such as linoleic acid effectively inhibit of Ca(2+) responses in mast cells stimulated by antigen-mediated crosslinking of FcepsilonRI or by the SERCA pump inhibitor, thapsigargin. Linoleic Acid 179-192 Fc epsilon receptor Ia Homo sapiens 294-305 24769339-6 2014 Moreover, we find that linoleic acid induces some STIM1-STIM1 association, while inhibiting stimulated STIM1 oligomerization that precedes STIM1-Orai1 coupling. Linoleic Acid 23-36 stromal interaction molecule 1 Homo sapiens 50-55 24769339-6 2014 Moreover, we find that linoleic acid induces some STIM1-STIM1 association, while inhibiting stimulated STIM1 oligomerization that precedes STIM1-Orai1 coupling. Linoleic Acid 23-36 stromal interaction molecule 1 Homo sapiens 56-61 24769339-6 2014 Moreover, we find that linoleic acid induces some STIM1-STIM1 association, while inhibiting stimulated STIM1 oligomerization that precedes STIM1-Orai1 coupling. Linoleic Acid 23-36 stromal interaction molecule 1 Homo sapiens 56-61 24769339-6 2014 Moreover, we find that linoleic acid induces some STIM1-STIM1 association, while inhibiting stimulated STIM1 oligomerization that precedes STIM1-Orai1 coupling. Linoleic Acid 23-36 stromal interaction molecule 1 Homo sapiens 56-61 24769339-6 2014 Moreover, we find that linoleic acid induces some STIM1-STIM1 association, while inhibiting stimulated STIM1 oligomerization that precedes STIM1-Orai1 coupling. Linoleic Acid 23-36 ORAI calcium release-activated calcium modulator 1 Homo sapiens 145-150 24769339-7 2014 We hypothesize that linoleic acid and related PUFAs inhibit STIM1-Orai1 coupling by a mechanism that involves perturbation of ER membrane structure, possibly by disrupting electrostatic interactions important in STIM1 oligomerization. Linoleic Acid 20-33 stromal interaction molecule 1 Homo sapiens 60-65 24769339-7 2014 We hypothesize that linoleic acid and related PUFAs inhibit STIM1-Orai1 coupling by a mechanism that involves perturbation of ER membrane structure, possibly by disrupting electrostatic interactions important in STIM1 oligomerization. Linoleic Acid 20-33 ORAI calcium release-activated calcium modulator 1 Homo sapiens 66-71 24769339-7 2014 We hypothesize that linoleic acid and related PUFAs inhibit STIM1-Orai1 coupling by a mechanism that involves perturbation of ER membrane structure, possibly by disrupting electrostatic interactions important in STIM1 oligomerization. Linoleic Acid 20-33 stromal interaction molecule 1 Homo sapiens 212-217 24769339-7 2014 We hypothesize that linoleic acid and related PUFAs inhibit STIM1-Orai1 coupling by a mechanism that involves perturbation of ER membrane structure, possibly by disrupting electrostatic interactions important in STIM1 oligomerization. Fatty Acids, Unsaturated 46-51 stromal interaction molecule 1 Homo sapiens 60-65 24769339-7 2014 We hypothesize that linoleic acid and related PUFAs inhibit STIM1-Orai1 coupling by a mechanism that involves perturbation of ER membrane structure, possibly by disrupting electrostatic interactions important in STIM1 oligomerization. Fatty Acids, Unsaturated 46-51 ORAI calcium release-activated calcium modulator 1 Homo sapiens 66-71 24769339-7 2014 We hypothesize that linoleic acid and related PUFAs inhibit STIM1-Orai1 coupling by a mechanism that involves perturbation of ER membrane structure, possibly by disrupting electrostatic interactions important in STIM1 oligomerization. Fatty Acids, Unsaturated 46-51 stromal interaction molecule 1 Homo sapiens 212-217