PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2458948-0 1988 Transcriptional and post-transcriptional regulation of c-myc, c-myb, and p53 during proliferation and differentiation of murine erythroleukemia cells treated with DFMO and DMSO. Eflornithine 163-167 myeloblastosis oncogene Mus musculus 62-67 2458948-0 1988 Transcriptional and post-transcriptional regulation of c-myc, c-myb, and p53 during proliferation and differentiation of murine erythroleukemia cells treated with DFMO and DMSO. Eflornithine 163-167 transformation related protein 53, pseudogene Mus musculus 73-76 2458948-0 1988 Transcriptional and post-transcriptional regulation of c-myc, c-myb, and p53 during proliferation and differentiation of murine erythroleukemia cells treated with DFMO and DMSO. Dimethyl Sulfoxide 172-176 myeloblastosis oncogene Mus musculus 62-67 2458948-0 1988 Transcriptional and post-transcriptional regulation of c-myc, c-myb, and p53 during proliferation and differentiation of murine erythroleukemia cells treated with DFMO and DMSO. Dimethyl Sulfoxide 172-176 transformation related protein 53, pseudogene Mus musculus 73-76 2458948-4 1988 In contrast, treatment of the cells with DFMO resulted in gradual cessation of cell replication and a decrease in transcription of c-myc, c-myb and p53. Eflornithine 41-45 myeloblastosis oncogene Mus musculus 138-143 2458948-4 1988 In contrast, treatment of the cells with DFMO resulted in gradual cessation of cell replication and a decrease in transcription of c-myc, c-myb and p53. Eflornithine 41-45 transformation related protein 53, pseudogene Mus musculus 148-151 2458948-5 1988 When the MEL cells were induced to differentiate with dimethyl sulfoxide (DMSO), a transient reduction in c-myc and c-myb RNA levels occurred immediately prior to the G1 arrest with a concomitant decrease in transcriptional activity, while p53 mRNA production was elevated without an increase in transcription. Dimethyl Sulfoxide 54-72 myeloblastosis oncogene Mus musculus 116-121 2458948-5 1988 When the MEL cells were induced to differentiate with dimethyl sulfoxide (DMSO), a transient reduction in c-myc and c-myb RNA levels occurred immediately prior to the G1 arrest with a concomitant decrease in transcriptional activity, while p53 mRNA production was elevated without an increase in transcription. Dimethyl Sulfoxide 54-72 transformation related protein 53, pseudogene Mus musculus 240-243 2458948-5 1988 When the MEL cells were induced to differentiate with dimethyl sulfoxide (DMSO), a transient reduction in c-myc and c-myb RNA levels occurred immediately prior to the G1 arrest with a concomitant decrease in transcriptional activity, while p53 mRNA production was elevated without an increase in transcription. Dimethyl Sulfoxide 74-78 myeloblastosis oncogene Mus musculus 116-121 2458948-5 1988 When the MEL cells were induced to differentiate with dimethyl sulfoxide (DMSO), a transient reduction in c-myc and c-myb RNA levels occurred immediately prior to the G1 arrest with a concomitant decrease in transcriptional activity, while p53 mRNA production was elevated without an increase in transcription. Dimethyl Sulfoxide 74-78 transformation related protein 53, pseudogene Mus musculus 240-243 2458948-7 1988 From these experiments we conclude that (i) c-myc, c-myb, and p53 are regulated independently at both the transcriptional and post-transcriptional levels, (ii) DFMO inhibits MEL cell proliferation and expression of several genes, including c-myc, c-myb and p53, and (iii) DFMO suppresses terminal differentiation but is unable to alter proto-oncogene changes associated with the early stages of differentiation. Eflornithine 160-164 myeloblastosis oncogene Mus musculus 51-56 2458948-7 1988 From these experiments we conclude that (i) c-myc, c-myb, and p53 are regulated independently at both the transcriptional and post-transcriptional levels, (ii) DFMO inhibits MEL cell proliferation and expression of several genes, including c-myc, c-myb and p53, and (iii) DFMO suppresses terminal differentiation but is unable to alter proto-oncogene changes associated with the early stages of differentiation. Eflornithine 160-164 transformation related protein 53, pseudogene Mus musculus 62-65 2458948-7 1988 From these experiments we conclude that (i) c-myc, c-myb, and p53 are regulated independently at both the transcriptional and post-transcriptional levels, (ii) DFMO inhibits MEL cell proliferation and expression of several genes, including c-myc, c-myb and p53, and (iii) DFMO suppresses terminal differentiation but is unable to alter proto-oncogene changes associated with the early stages of differentiation. Eflornithine 160-164 myeloblastosis oncogene Mus musculus 247-252 2458948-7 1988 From these experiments we conclude that (i) c-myc, c-myb, and p53 are regulated independently at both the transcriptional and post-transcriptional levels, (ii) DFMO inhibits MEL cell proliferation and expression of several genes, including c-myc, c-myb and p53, and (iii) DFMO suppresses terminal differentiation but is unable to alter proto-oncogene changes associated with the early stages of differentiation. Eflornithine 160-164 transformation related protein 53, pseudogene Mus musculus 257-260