PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24220725-0 2014 Extract of Bryophyllum laetivirens reverses etoposide resistance in human lung A549 cancer cells by downregulation of NF-kappaB. Etoposide 44-53 nuclear factor kappa B subunit 1 Homo sapiens 118-127 24220725-3 2014 We first found that lung cancer A549 cells resistant to etoposide (A549RT-eto) exhibit upregulation of NF-kappaB and SIRT1 in comparison to A549 parental cells. Etoposide 56-65 nuclear factor kappa B subunit 1 Homo sapiens 103-112 24220725-10 2014 Taken together, we suggest that upregulation of NF-kappaB determines etoposide resistance through P-gp expression in human A549 lung cancer cells. Etoposide 69-78 nuclear factor kappa B subunit 1 Homo sapiens 48-57 24220725-11 2014 We herein demonstrated that B. laetivirens extract reverses etoposide resistance in human A549 lung cancer cells through downregulation of NF-kappaB. Etoposide 60-69 nuclear factor kappa B subunit 1 Homo sapiens 139-148