PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24099794-1 2013 The successful clinical management of lung cancer is limited by frequent loss-of-function mutations in p53 which cooperates with chronic oxidant-stress induced adaptations in mercapturic acid pathway (MAP) which in turn regulates critical intracellular signaling cascades that determine therapeutic refractoriness. Acetylcysteine 175-191 tumor protein p53 Homo sapiens 103-106