PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24005046-4	2013	We examined the effects of azelastine on the hERG channels expressed in Xenopus oocytes and HEK293 cells using two-microelectrode voltage-clamp and patch-clamp techniques.	azelastine	27-37	ETS transcription factor ERG	Homo sapiens	45-49	
24005046-5	2013	Azelastine induced a concentration-dependent decrease of the hERG current amplitude at the end of the voltage steps and tail currents.	azelastine	0-10	ETS transcription factor ERG	Homo sapiens	61-65	
24005046-6	2013	The IC50 for the azelastine-induced block of the hERG currents expressed in HEK293 cells was 11.43 nM, while the drug inhibited I(Ca,L) and I(Ca,T) with IC50 values of 7.60 and 26.21 muM, respectively.	azelastine	17-27	ETS transcription factor ERG	Homo sapiens	49-53	
24005046-8	2013	These results suggest that azelastine is a potent blocker of hERG channels rather than I(Ca,L) or I(Ca,T), providing molecular mechanisms for the arrhythmogenic side effects during the clinical administration of azelastine.	azelastine	27-37	ETS transcription factor ERG	Homo sapiens	61-65	
24005046-8	2013	These results suggest that azelastine is a potent blocker of hERG channels rather than I(Ca,L) or I(Ca,T), providing molecular mechanisms for the arrhythmogenic side effects during the clinical administration of azelastine.	azelastine	212-222	ETS transcription factor ERG	Homo sapiens	61-65