PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23752175-0 2013 Genome-wide studies in multiple myeloma identify XPO1/CRM1 as a critical target validated using the selective nuclear export inhibitor KPT-276. KPT-276 135-142 exportin 1 Homo sapiens 49-53 23752175-0 2013 Genome-wide studies in multiple myeloma identify XPO1/CRM1 as a critical target validated using the selective nuclear export inhibitor KPT-276. KPT-276 135-142 exportin 1 Homo sapiens 54-58 23752175-6 2013 A selective inhibitor of nuclear export compound KPT-276 specifically and irreversibly inhibits the nuclear export function of XPO1. KPT-276 49-56 exportin 1 Homo sapiens 127-131 23752175-10 2013 Western blotting and reverse transcription-PCR confirm that c-MYC, CDC25A and BRD4 are all downregulated after treatment with KPT-276. KPT-276 126-133 MYC proto-oncogene, bHLH transcription factor Homo sapiens 60-65 23752175-10 2013 Western blotting and reverse transcription-PCR confirm that c-MYC, CDC25A and BRD4 are all downregulated after treatment with KPT-276. KPT-276 126-133 cell division cycle 25A Homo sapiens 67-73 23752175-10 2013 Western blotting and reverse transcription-PCR confirm that c-MYC, CDC25A and BRD4 are all downregulated after treatment with KPT-276. KPT-276 126-133 bromodomain containing 4 Homo sapiens 78-82